It is generally considered advisable to use another diuretic in patients whose hearing is already impaired, and to avoid using furosemide along with other ototoxic drugs, such as the aminoglycosides.
Cope, ... T.D. Brain. Rick M. Fairhurst, Thomas E. Wellems, in Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases (Eighth Edition), 2015, The combination of quinine plus doxycycline is effective against multidrug-resistant parasites. They seem to die of the complications (e.g., trauma, intercurrent infections, malnutrition) that occur at much increased risk . About 60 cases of ototoxicity to the developing human fetus have been reported from treatment of the mother during pregnancy with any of several aminoglycoside antibiotics (Schardein, 1993).
Indeed, for centuries “senile dementia” was viewed by some as a concomitant of aging, and not as a disease. "It's not you, it's your brain." —
Cortical thickness in congenital amusia: When less is better than more. (Oct. 26, 2009)http://www.nidcd.nih.gov/tunetest/, Society for Neuroscience.
“I am Stella and my car is called Steve,” BENEE explains. Oxford, Oxfordshire, Experiments for the social good
Aug. 26, 2007.http://www.sciencedaily.com/releases/2007/08/070823214755.htm, Montreal Neurological Institute and Hospital. Functional neuroimaging data also demonstrate similar activation patterns in both right and left auditory cortices across groups, but reveal a decreased level of activity in the inferior frontal gyrus (IFG) in amusics compared to normal controls. Indeed, excellence in one may go with mediocrity, even total incompetence in another.
We now recognize that congenital (developmental) amusia is a disorder characterized by a failure to recognize familiar tunes, to distinguish one tune from another. But it is absurd to suppose the several types of fitness to be totally unconnected. Taking a tone-deaf test may help you finally figure out if you’re an untrained future talent, or if you are physically unable to perceive the difference in musical notes.
When the onset of disease is late, the patient shows the characteristic multiplex pathology so familiar to the geriatrician: damage in several body systems, so that it is often difficult to say which is the final cause of death. Drugs included are streptomycin, dihydrostreptomycin, kanamycin, and probably gentamicin. Individuals with congenital amusia (tone-deafness) are developmentally unable to differentiate between pitches that are close in frequency.
I wasn’t going to watch Bird Box. 6.
2, 2007.http://www.independent.co.uk/student/magazines/amusia-sufferers-cant-name-that-tune-443038.html, Bernal, Byron; Ardila, Alfredo. Of the 57 neonates who had received furosemide nine had a subsequent abnormal hearing screen, and of the 207 neonates who had not received furosemide 33 also had an abnormal hearing screen. If you haven't seen Bird Box and still plan on watching it, don't read this. The apparent opposite of congenital amusia is absolute pitch (AP), the ability to identify or demonstrate a pitch in the absence of a reference tone. MBEA “assesses the different components that are known to be involved in melody processing of Western tonal music: pitch contour, musical scales, pitch intervals, rhythm, meter, and memory” (Peretz, 2008). It is useful to distinguish between the unfolding of a disease and the impact of its complications.
Additionally, amusics have more recently been shown to have an increase in the cortical thickness of the IFG, with researchers speculating that the combination of white and gray matter differences represents inefficient, abnormal connections leading to the functional deficit. "Tone deafness explained." (Modified from Jones, J, Zalewski, C, Brewer, C, Lucker, J and Drayna, D (2009) Widespread auditory deficits in tune deafness. An important adverse effect of quinine treatment in severe malaria is hypoglycemia.170,171 Pregnant women are particularly susceptible to this complication.172 All patients receiving quinine or quinidine should be monitored for hypoglycemia, and any deterioration in clinical status (including seizures or altered mental status) should prompt assessment of plasma glucose.
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